DPCstruct | MC24257

Metacluster Properties and Pfam Annotations

Number of structural domains67
Mean domain length (aa)86 ± 7 aa
Standard deviation of domain lengths6.64
Length coefficient of variation0.08
Mean AlphaFold2 pLDDT confidence score88.52
Mean fraction of residues predicted as intrinsically disordered0.46
Mean length-normalized TM-Score0.72
Mean intra-cluster local Distance Difference Test score0.69
Mean intra-cluster sequence similarity (%)37.31
Pfam Score0.00
Assigned Pfam label(s) UNKNOWN

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A2D8BYX6 82-160 MYRGEKFPGLNKPKRAPKGSKKKYRVLAHQKGKYKIVSFGARGYKDFLQHKNKKRRSNFKSRHNCDKKKNKLTAGYWAC
A0A6C0BYU8 479-578 KERIIKFMRGPGEKKYTARIMHKKTRKIRHIHFGAKGYEQFKDSTPLGLYSSKNHGTKKRRDNYFSRHSGIKNKKKALAKEIRKSKG…
A0A2E7V4J8 79-160 None
A0A3R7S3D1 19-107 None
A0A080Z461 188-271 None
A0A7Y1VPG0 14-106 None
A0A6C0H3A0 8-92 None
A0A6C0H0X1 1-83 None
A0A2E0BR58 39-123 None
A0A6C0IA48 149-237 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.