DPCstruct | MC24254

Metacluster Properties and Pfam Annotations

Number of structural domains25
Mean domain length (aa)117 ± 18 aa
Standard deviation of domain lengths17.66
Length coefficient of variation0.15
Mean AlphaFold2 pLDDT confidence score83.36
Mean fraction of residues predicted as intrinsically disordered0.18
Mean length-normalized TM-Score0.67
Mean intra-cluster local Distance Difference Test score0.60
Mean intra-cluster sequence similarity (%)17.38
Pfam Score0.00
Assigned Pfam label(s) UNKNOWN

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A327KFU2 3-105 DRVGKLLEQFGRHDSLLEMGDYSIYGDYWGFPQVKVTVENLKLLRPDIVERLQGVVADFPGWEIVVAVAVPEHISDWPDMGLYIRPH…
A0A3C1ASM2 23-127 VINSPEDEAAFISEWDGVRERLMQTLDALGEWNAYGEGDYYIGDQVMQSRGIGIELTSDMMLDKKLIPLIQSSLHGCTSSYEVYCSF…
A0A5C5XD53 67-203 None
A0A7T9IM81 116-216 None
A2SCP6 2-100 None
A0A366HGY4 27-128 None
A0A5Q3LB85 1-156 None
A0A2S0NFL7 8-127 None
A0A8A7V7A1 65-158 None
A0A0S3PZC5 7-121 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.