DPCstruct | MC24237

Metacluster Properties and Pfam Annotations

Number of structural domains27
Mean domain length (aa)165 ± 17 aa
Standard deviation of domain lengths16.78
Length coefficient of variation0.10
Mean AlphaFold2 pLDDT confidence score80.48
Mean fraction of residues predicted as intrinsically disordered0.28
Mean length-normalized TM-Score0.73
Mean intra-cluster local Distance Difference Test score0.63
Mean intra-cluster sequence similarity (%)21.78
Pfam Score100.00
Assigned Pfam label(s) PF15639

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A7W5TZA4 1-147 MIVAPAFVKQYPRLATWICDNLPRVKDKQKVFRAFQKYSRLNEKVSERALQHGNPPTIEYRYLPADNGIFIGNKYPGTVFLSMSICD…
A0A1G9Q2D9 3-169 MDAKAIREYPYLDAFLRGLGDRVARNPTVQKAFRDASTVVDAVADQALVFGNDPGVLPGDIGARYGRYDPAKARTVIFIDQGFEQML…
A0A4R5F762 97-275 None
A0A1I2JB94 148-311 None
A0A2P8D0X7 121-311 None
A0A4U1CUK7 72-250 None
A0A2W7HEB2 7-145 None
A0A4Q8UA70 4-150 None
A0A3C1RD73 165-317 None
A0A2N3T3C6 483-651 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.