DPCstruct | MC2422

Metacluster Properties and Pfam Annotations

Number of structural domains24
Mean domain length (aa)68 ± 4 aa
Standard deviation of domain lengths3.79
Length coefficient of variation0.06
Mean AlphaFold2 pLDDT confidence score75.73
Mean fraction of residues predicted as intrinsically disordered0.30
Mean length-normalized TM-Score0.69
Mean intra-cluster local Distance Difference Test score0.85
Mean intra-cluster sequence similarity (%)46.24
Pfam Score0.00
Assigned Pfam label(s) UNKNOWN

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A015KL31 1-64 MSEAVSTFTTGNVSLTLADEIKKYKTDALIKFLQREEDLELDDDNLKVIREEKVNGRDFLKLTE
A0A2Z6SQK2 1-72 MSKTSTPYTPASTSTTVTGNEMFSLADEIKKYKMKELIDFLRKKKDLGLDDDDLEIFRKRKIAGRTFLKMDK
A0A397SPL3 1-66 None
A0A372Q4E0 1-65 None
A0A372QPM1 1-66 None
A0A2Z6RGN9 53-123 None
A0A2Z6RL25 1-62 None
A0A2H5S761 1-65 None
A0A397J6L1 23-93 None
A0A2N1N6K8 45-106 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.