DPCstruct | MC24194

Metacluster Properties and Pfam Annotations

Number of structural domains15
Mean domain length (aa)133 ± 29 aa
Standard deviation of domain lengths28.68
Length coefficient of variation0.22
Mean AlphaFold2 pLDDT confidence score67.73
Mean fraction of residues predicted as intrinsically disordered0.48
Mean length-normalized TM-Score0.49
Mean intra-cluster local Distance Difference Test score0.74
Mean intra-cluster sequence similarity (%)39.91
Pfam Score0.00
Assigned Pfam label(s) UNKNOWN

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A4S8I8V6 293-389 VENTAFVLATERTRRRDPLNGFKLYNGGWNISDLHYLASVGFTAAPLFAVAAVWFFGFALVLSLICCCYCCFPRRSCSFSRTTCALS…
A0A0D9YNC7 13-148 LLLLLIVLSLVVLAALLAAAAADASAVAGGGRSSPSTTTFVLAGERTRRKDPLDGLRLYSGGWNISDEHYWASVGFTAAPVFAAAAI…
A0A822YHN6 50-164 None
A0A4S8JBB7 12-173 None
A0A834Z731 22-131 None
A0A445EMQ1 7-118 None
A0A2P6RIH5 16-158 None
A0A287NBN6 5-146 None
A0A2I0VXX2 1-169 None
A0A7J6GZE1 56-167 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.