DPCstruct | MC24181

Metacluster Properties and Pfam Annotations

Number of structural domains216
Mean domain length (aa)198 ± 26 aa
Standard deviation of domain lengths25.65
Length coefficient of variation0.13
Mean AlphaFold2 pLDDT confidence score77.43
Mean fraction of residues predicted as intrinsically disordered0.22
Mean length-normalized TM-Score0.59
Mean intra-cluster local Distance Difference Test score0.57
Mean intra-cluster sequence similarity (%)17.28
Pfam Score99.66
Assigned Pfam label(s) PF02759- CL0321

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A2FWW6 693-856 None
E4Y1S4 6-243 None
A0A672YN02 158-387 None
S9WLN0 7-216 None
E3MP61 123-317 None
A0A2A2K4B1 1-217 None
A0A812ATF4 1-189 None
A0A5K3EIS2 398-588 None
A0A183KPK8 91-300 None
J9EQJ5 486-683 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.