DPCstruct | MC24158

Metacluster Properties and Pfam Annotations

Number of structural domains6
Mean domain length (aa)71 ± 6 aa
Standard deviation of domain lengths6.37
Length coefficient of variation0.09
Mean AlphaFold2 pLDDT confidence score85.38
Mean fraction of residues predicted as intrinsically disordered0.39
Mean length-normalized TM-Score0.70
Mean intra-cluster local Distance Difference Test score0.80
Mean intra-cluster sequence similarity (%)35.60
Pfam Score0.00
Assigned Pfam label(s) UNKNOWN

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A4U9EVG9 43-111 RDDNVNLMDAGVRRARVERERANLMANHECTHDNWKSRQGPHQCEECYDVLPVFIYECRQCHTMACRRC
A0A3A2ZLV3 1-78 MPRNANNADRRNAFNRAVNSLQQHENVSCNHQKDDQWAFRSRGSMECEICHDILPEYVFMCRNCLMKVCASCRRNRLR
A0A818Z053 204-272 None
A0A484FB81 866-931 None
A0A1J8PS29 1-80 None
A0A2S4L136 507-568 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.