DPCstruct | MC24156

Metacluster Properties and Pfam Annotations

Number of structural domains232
Mean domain length (aa)515 ± 140 aa
Standard deviation of domain lengths140.22
Length coefficient of variation0.27
Mean AlphaFold2 pLDDT confidence score79.58
Mean fraction of residues predicted as intrinsically disordered0.21
Mean length-normalized TM-Score0.64
Mean intra-cluster local Distance Difference Test score0.64
Mean intra-cluster sequence similarity (%)26.24
Pfam Score96.73
Assigned Pfam label(s) CL0023- PF01576- CL0378- CL0220- CL0072

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A183VF33 47-434 LKAELVQEMNPPKFEKTEDMSNLTFLNDASVLHNLRARYGSMLIYTYSGLFCVVINPYKRLPIYTDSVASMFMGKRRTEMPPHLFAV…
A0A3A2ZGN6 30-564 VSTTTLLNALHSFYTAGQPYQLDAGTSLVVNSWLTATRTTPDGSNGSTIDRDLARRAWEHARRRAEDGCIVLCSTHQSTPSLLEPYL…
A0A6S8WDV1 220-1000 None
A0A6A2XZH7 275-661 None
A0A5E4QE36 1-403 None
G4TZ95 19-330 None
U6L5B2 6-405 None
A0A6P6C304 8-489 None
A0A553MZB0 142-519 None
A0A7S1V7N4 1-496 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.