DPCstruct | MC24131

Metacluster Properties and Pfam Annotations

Number of structural domains1527
Mean domain length (aa)168 ± 26 aa
Standard deviation of domain lengths25.78
Length coefficient of variation0.15
Mean AlphaFold2 pLDDT confidence score76.86
Mean fraction of residues predicted as intrinsically disordered0.29
Mean length-normalized TM-Score0.35
Mean intra-cluster local Distance Difference Test score0.46
Mean intra-cluster sequence similarity (%)12.10
Pfam Score38.15
Assigned Pfam label(s) PF10272- PF20456- PF19124- CL0028- CL0425

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A4Q2S4A0 165-325 None
A0A5J4KWK5 24-193 None
A0A443YN56 10-189 None
C4RFC6 106-261 None
R9T804 17-182 None
A0A2E7C6P2 1-161 None
A0A2W5NEF7 11-192 None
A0A255ZUK6 16-145 None
A0A2W6AIL3 20-192 None
A0A1Q3K7N1 51-258 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.