DPCstruct | MC24084

Metacluster Properties and Pfam Annotations

Number of structural domains120
Mean domain length (aa)172 ± 27 aa
Standard deviation of domain lengths27.23
Length coefficient of variation0.16
Mean AlphaFold2 pLDDT confidence score89.82
Mean fraction of residues predicted as intrinsically disordered0.22
Mean length-normalized TM-Score0.72
Mean intra-cluster local Distance Difference Test score0.67
Mean intra-cluster sequence similarity (%)26.61
Pfam Score86.44
Assigned Pfam label(s) CL0187- PF04294- CL0593

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A7K0NA41 9-217 GITQKISSFTQQFPYAAYRVQNIGEAARRVNGTLLMPGETFSMNDTIKERTVANGYTVGFVIGAGGVFAEELGGGVSAATTTMWTAA…
A0A7J6Z4G9 250-435 QISTSQEIKSNAYFANKIHNIDLAIQTLNGVIIQPQQIFSFWHLVKAPTLKNGYKAGRNLVNGVISEDLGGGICQISSSLYISALKA…
A0A6L6GVJ3 169-351 None
A0A521TRE7 121-356 None
A0A347AIJ7 190-328 None
A0A1C5JNH0 15-157 None
A0A6B8RP06 124-278 None
A0A7H5F0I5 37-198 None
R6VZ25 151-308 None
A0A399ESR1 131-310 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.