DPCstruct | MC24081

Metacluster Properties and Pfam Annotations

Number of structural domains40
Mean domain length (aa)353 ± 55 aa
Standard deviation of domain lengths54.94
Length coefficient of variation0.16
Mean AlphaFold2 pLDDT confidence score74.53
Mean fraction of residues predicted as intrinsically disordered0.23
Mean length-normalized TM-Score0.54
Mean intra-cluster local Distance Difference Test score0.49
Mean intra-cluster sequence similarity (%)15.05
Pfam Score59.68
Assigned Pfam label(s) PF14778- PF20908

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A1S0U355 2-353 WKVDFDHLFENYRNNSRYQENGTVAALLFGNASLANITNVLFGCLSDFDATLDLIRFIESSLPSNITFLGVLSLVNVEYPFDLNSLA…
A0A7J6YYK4 295-638 QFVRLINVKEPSRGNIYGILHSNTLVVVGVYIQDEDKTDITQGFPTEIDIYGVIQIGNEAIDEEKIKQILNEVDVTDTPLYITCKFD…
A0A0N4TMH4 471-834 None
A0A7S2MTW2 8-348 None
L8H7J7 1-425 None
E9J0W0 43-348 None
H2N4D3 1-312 None
A0A0D2MD53 4-391 None
A0A3Q0J8G8 50-396 None
A0A2B4SEQ3 5-361 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.