DPCstruct | MC24068

Metacluster Properties and Pfam Annotations

Number of structural domains19
Mean domain length (aa)104 ± 17 aa
Standard deviation of domain lengths16.55
Length coefficient of variation0.16
Mean AlphaFold2 pLDDT confidence score83.86
Mean fraction of residues predicted as intrinsically disordered0.23
Mean length-normalized TM-Score0.81
Mean intra-cluster local Distance Difference Test score0.77
Mean intra-cluster sequence similarity (%)26.53
Pfam Score0.00
Assigned Pfam label(s) UNKNOWN

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A431HQL2 183-277 FPRKELQHSEFVMLNTQMAKELLAAVWTEQDGNRKVKYNVKEAYKRDILNDCWIPSDESIGIDYNHVVYNGRHRLTALIESEKEWPF…
A0A3M7LG70 84-177 VVQTTLKHATIFISPQLARNMLTFSSRGSVNKKNKNRRLSKIKVRKYAESMKRREWCLTGEPIIISYEGEILNGHHRLEAACEACVG…
A0A7Y0MWW1 79-175 None
A0A0F9YBN8 2-115 None
I6AWV0 8-157 None
A0A2D6W217 77-160 None
A0A0F9BU72 6-109 None
A0A6I1JY39 1-131 None
A0A1H2DWM1 24-112 None
A0A1X2YR41 299-414 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.