DPCstruct | MC24051

Metacluster Properties and Pfam Annotations

Number of structural domains129
Mean domain length (aa)108 ± 22 aa
Standard deviation of domain lengths22.09
Length coefficient of variation0.20
Mean AlphaFold2 pLDDT confidence score88.68
Mean fraction of residues predicted as intrinsically disordered0.25
Mean length-normalized TM-Score0.74
Mean intra-cluster local Distance Difference Test score0.70
Mean intra-cluster sequence similarity (%)26.29
Pfam Score89.20
Assigned Pfam label(s) PF03900- CL0177

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
B7FFZ8 112-211 MLPAVAQGAIGIACRSNDDKMAEYLASLNHEETRLAISCERAFLTTLDGSCRTPIAGYASRDKDGNCLFRGLVASPDGTRVLETSRI…
A0A7C3ILI3 247-338 RTDDYRVINIVSVLDDPVTHCAVAAERAFLAALGGGCRRPIGVYGELRDEQLHLYGRIIDEHSNAVIEGKISGRSQECEVIAQNLAR…
K3W5I8 455-560 None
A0A3D1QYZ5 64-177 None
A0A7Y2D1J8 564-669 None
A0A7C7V706 1-83 None
Q1HRH6 7-108 None
A0A848V8K2 2-67 None
A0A2N9G934 959-1057 None
A0A183SL25 187-318 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.