DPCstruct | MC24004

Metacluster Properties and Pfam Annotations

Number of structural domains20
Mean domain length (aa)210 ± 70 aa
Standard deviation of domain lengths70.13
Length coefficient of variation0.33
Mean AlphaFold2 pLDDT confidence score91.15
Mean fraction of residues predicted as intrinsically disordered0.20
Mean length-normalized TM-Score0.81
Mean intra-cluster local Distance Difference Test score0.76
Mean intra-cluster sequence similarity (%)43.66
Pfam Score100.00
Assigned Pfam label(s) CL0179

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A2P8DAU4 50-401 EGIRYYVKRGVTELLVQKKYMGSYCDIYLHRDLDATYFVSRNGHLIQHIDLEAARQACQAMHARLDWDGVQLVIIQAEMMPWSILGK…
A0A7W1PH27 124-347 LPEAVAVAGRAAKRGLDVGALVERFTTRASLVERYTAAWQRYCWPVTSVADLKLAPFHVLATQGAVHADKDHRWHMETAASICGADD…
W7YXD7 22-145 None
A0A2S2BVN2 249-553 None
A0A7C3J7Q2 1-122 None
A0A7W0RNH7 899-1126 None
A7C1P4 278-500 None
A0A516PWY4 54-200 None
A0A384IRY3 1045-1269 None
A0A1G8CZU5 68-223 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.