DPCstruct | MC24

Metacluster Properties and Pfam Annotations

Number of structural domains45
Mean domain length (aa)189 ± 41 aa
Standard deviation of domain lengths40.75
Length coefficient of variation0.22
Mean AlphaFold2 pLDDT confidence score86.25
Mean fraction of residues predicted as intrinsically disordered0.28
Mean length-normalized TM-Score0.57
Mean intra-cluster local Distance Difference Test score0.65
Mean intra-cluster sequence similarity (%)23.60
Pfam Score100.00
Assigned Pfam label(s) PF16593- CL0693

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
L1NEL7 1-176 MGKKVLGLDLGVGSIGWCLITLDKDEKPQSILGMGSRIVPLSADDATEFTQGKAITKNKMRTVARTIRKGMDRYQLRREALKKVLRE…
A0A377L925 4-216 DYTIGLDIGTNSVGWAVITDEYRLMAKKMSIHGNTEKKKVKKNFWGARLFDEGQTAEARRSKRTTRRRLMRRRYRILELQKIFAEEI…
A0A1E5INB4 1-206 None
B1GZ56 19-164 None
A0A316QB55 3-225 None
A0A3F3H306 1-209 None
A0A380JD47 17-245 None
A0A3N0I2S3 4-132 None
A0A1H9D582 1-169 None
A0A0Q4IQB3 1-169 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.