DPCstruct | MC23998

Metacluster Properties and Pfam Annotations

Number of structural domains756
Mean domain length (aa)137 ± 24 aa
Standard deviation of domain lengths23.81
Length coefficient of variation0.17
Mean AlphaFold2 pLDDT confidence score79.68
Mean fraction of residues predicted as intrinsically disordered0.23
Mean length-normalized TM-Score0.47
Mean intra-cluster local Distance Difference Test score0.47
Mean intra-cluster sequence similarity (%)13.05
Pfam Score96.07
Assigned Pfam label(s) PF13511- CL0750- CL0159- CL0353

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A2V4AFR5 2-74 VIKADKIVYGTISELDSTTLTLKIEGSLTNDSGTLKIERFEDWTCASRWTEYKIGQRVFLFLTSWKGKLIAMS
A0A644YWU4 47-180 FSNKISLRTYKISHSWAIDIKDPKQVYDNSDFIFIGTVEKQVGTITYGNFPETQFSVIVHQLIKGNIKDTIVVNQEGGIKNYTLTIA…
A0A7C1EBX7 10-141 None
A0A6A5DGM3 270-409 None
A0A368FA52 37-154 None
A0A7W1YMD1 2-140 None
L9KKJ8 86-204 None
A0A7T2GLK4 144-259 None
A0A358EQ10 13-148 None
A0A5J5CHL1 272-445 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.