DPCstruct | MC23995

Metacluster Properties and Pfam Annotations

Number of structural domains11
Mean domain length (aa)124 ± 10 aa
Standard deviation of domain lengths9.87
Length coefficient of variation0.08
Mean AlphaFold2 pLDDT confidence score90.36
Mean fraction of residues predicted as intrinsically disordered0.17
Mean length-normalized TM-Score0.78
Mean intra-cluster local Distance Difference Test score0.75
Mean intra-cluster sequence similarity (%)26.42
Pfam Score0.00
Assigned Pfam label(s) UNKNOWN

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A7L4PL83 75-207 IIRILKKEGHLKGELSETDIERIKTRVNLATNWVKLYAPDMIKFEILTEAPKVDLSKEQREGLKIISDLIQGEDLTDVELHNKIYEI…
A0A644YLE8 1-122 MTDSQKQRLRTRCTCAWNWITTFAPEDFKYRLSNENDPKVELTEQELKAVKALYQVVEVMDQLEDKEYTTRLYDAAKLNDLDTGEFF…
A0A5E4I4S9 649-776 None
A0A822IVL3 180-301 None
A0A256Y079 597-725 None
A0A1F3VMG3 259-382 None
A0A0L0LJ09 1-143 None
A0A1F7I819 432-556 None
A0A832ZF59 139-257 None
A0A843LJK4 141-259 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.