DPCstruct | MC23975

Metacluster Properties and Pfam Annotations

Number of structural domains37
Mean domain length (aa)77 ± 8 aa
Standard deviation of domain lengths8.24
Length coefficient of variation0.11
Mean AlphaFold2 pLDDT confidence score90.14
Mean fraction of residues predicted as intrinsically disordered0.19
Mean length-normalized TM-Score0.91
Mean intra-cluster local Distance Difference Test score0.88
Mean intra-cluster sequence similarity (%)49.32
Pfam Score100.00
Assigned Pfam label(s) CL0063

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A848SLA6 16-99 ARSLILATGARWRELGVPGEADYRNKGVAYCPHCDGPLFKGKRVAVVGGGNSGVEATIDLAGIVEHVTLIEFDANLRADEVLQA
A0A376MUC8 7-78 HAISGLPSEEAFKGRGVSACATCDGFFYRNQKVAVIGGGNTAVEEALYLSNIASEVHLIHRRDGFRAEKSLL
X1HMI4 1-55 None
A0A5N9CS94 197-277 None
N1QQ95 83-158 None
A0A7S2RHI1 92-176 None
A0A523RKD0 160-239 None
A0A523TWX7 151-231 None
A0A7J0E421 140-214 None
A0A0G0V3U4 108-188 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.