DPCstruct | MC2397

Metacluster Properties and Pfam Annotations

Number of structural domains22
Mean domain length (aa)127 ± 14 aa
Standard deviation of domain lengths14.05
Length coefficient of variation0.11
Mean AlphaFold2 pLDDT confidence score88.92
Mean fraction of residues predicted as intrinsically disordered0.25
Mean length-normalized TM-Score0.80
Mean intra-cluster local Distance Difference Test score0.85
Mean intra-cluster sequence similarity (%)43.47
Pfam Score0.00
Assigned Pfam label(s) UNKNOWN

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A812PXX2 562-689 MGQLLLTKRDQGELDWEQELAEALNRAEDRCLANCGRAPWGCRWFEEWRKNVDKAVELNQTLHVFYFESLAGHGKMAWHQLPDAKVR…
A0A813CAM7 1-149 AMGQLLLIKYPHTTHIEWREKQAEATEKALQLWQQSQGRAPWGCRWFELWKERVDEAVKLNQTLHVFYFKGRVGAGKLSWDQLGHDE…
A0A812QCC4 17-151 None
A0A813A176 124-231 None
A0A1Q9BYR2 684-811 None
A0A1Q9CBD6 544-686 None
A0A812L1N4 736-860 None
A0A812X2I3 187-314 None
A0A812VZJ9 156-283 None
A0A812Q8K7 296-440 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.