DPCstruct | MC23961

Metacluster Properties and Pfam Annotations

Number of structural domains60
Mean domain length (aa)168 ± 32 aa
Standard deviation of domain lengths31.57
Length coefficient of variation0.19
Mean AlphaFold2 pLDDT confidence score90.39
Mean fraction of residues predicted as intrinsically disordered0.23
Mean length-normalized TM-Score0.74
Mean intra-cluster local Distance Difference Test score0.68
Mean intra-cluster sequence similarity (%)24.79
Pfam Score88.24
Assigned Pfam label(s) PF01814- PF04405

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A2X1PQM2 3-142 DHIITRFHNRHREQLPELITLAEKVENVHGDRDDCPIGVTAQLEKIYAELSQHLMKEEQILFPMIKMGNYAMASMPIRVMEMEHDEA…
A0A4P6PJD6 193-383 WPETEAALLAVLEQRPEMDSTDWSSAPLSELIDHIVNTHHVFTKEQLPRLDGLLEKVQIAHGEHHGEMLGKLRLAYTAIRTELESHL…
E0I5F8 55-239 None
M0JI73 2-156 None
A0A0F9SRK3 51-240 None
A0A0D3LKG7 79-277 None
A0A7X7FE00 18-186 None
A0A5Q4DS87 22-152 None
A0A4P1K4H2 17-139 None
A0A1M4XKL7 7-154 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.