DPCstruct | MC2395

Metacluster Properties and Pfam Annotations

Number of structural domains19
Mean domain length (aa)524 ± 101 aa
Standard deviation of domain lengths100.81
Length coefficient of variation0.19
Mean AlphaFold2 pLDDT confidence score81.82
Mean fraction of residues predicted as intrinsically disordered0.22
Mean length-normalized TM-Score0.74
Mean intra-cluster local Distance Difference Test score0.69
Mean intra-cluster sequence similarity (%)29.56
Pfam Score95.24
Assigned Pfam label(s) PF16134- PF11732- PF11262

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A446NZT9 1-307 MELKCLFQYIVNQLKKGLGTELVVLEELIQQMANVQYTENMTDEQVDGMAGSETLRLQSSLFGSTRNYKVLNKSTNKLRDSLLPKDE…
A0A813C6P6 1-602 MAAASANSAAPSNRTLDDKLVAIIYKHLLPAISIAKPNPFLSSVAWNVLKQLTVFQRYMIYSCWETRYSQFMLKYSYEEAKFEAKKI…
A0A077ZF34 134-694 None
F4NSU7 589-1219 None
A0A180G634 3-420 None
B2KI97 451-1013 None
A0A835RQ69 1-349 None
A0A2C9JZK7 37-602 None
A0A2G9URE6 2-571 None
A0A1I8JQY3 72-499 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.