DPCstruct | MC2394

Metacluster Properties and Pfam Annotations

Number of structural domains47
Mean domain length (aa)89 ± 10 aa
Standard deviation of domain lengths10.14
Length coefficient of variation0.11
Mean AlphaFold2 pLDDT confidence score75.82
Mean fraction of residues predicted as intrinsically disordered0.38
Mean length-normalized TM-Score0.68
Mean intra-cluster local Distance Difference Test score0.81
Mean intra-cluster sequence similarity (%)43.81
Pfam Score88.89
Assigned Pfam label(s) CL0351- CL0072

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A154PMQ6 1-80 MTSYTFSKKSFKPTPPEKGSFPLDHEGLCKVVMLKYMRCLYENKNENTVCRNMAKDYLACRMDNQLMVQEDWSTIGYADQ
A0A813C3W5 35-127 MKLAVSMGKRIMPGRPPDKGSFPLDHFSECSKLKEEYLQCLKQHSHDNMSCRYLSKRYLQCRMDKNLMTKEPMERLGFTEEDVSPAP…
A0A2V0PJZ0 1-96 None
A0A4D6MKE1 1-91 None
A0A3P6RPG8 56-135 None
A0A094HWH7 370-484 None
A0A834QTI3 25-123 None
A0A811M1N4 129-222 None
A0A811MQB0 297-394 None
A0A2H6KC14 1-87 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.