DPCstruct | MC23921

Metacluster Properties and Pfam Annotations

Number of structural domains25
Mean domain length (aa)115 ± 10 aa
Standard deviation of domain lengths9.55
Length coefficient of variation0.08
Mean AlphaFold2 pLDDT confidence score84.70
Mean fraction of residues predicted as intrinsically disordered0.20
Mean length-normalized TM-Score0.85
Mean intra-cluster local Distance Difference Test score0.82
Mean intra-cluster sequence similarity (%)45.07
Pfam Score100.00
Assigned Pfam label(s) CL0020

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A2P2MB59 7-122 EDGEKWLAAGIAGLQQNAFYMHRALDSNNLRDALKYSAQMLSELRTSKLSPHKYYELYMRAFDELRKLELFFKEETRRGCSIVELYE…
A0A0D2L5I2 2-111 EEQDKFLKEASTSVKKNAYFMSKAMDEDNLREALRYSAAMLGELRTSYLSPQKYYELYMQVFDQLAHLESFFADEHAKGRTYSELYE…
A0A6P5VT95 7-131 None
A0A0R3T432 5-130 None
A0A3R6Z982 384-496 None
A0A6H5H135 6-115 None
A0A2I0KI66 6-103 None
A0A7J8CMZ3 3-119 None
B4I816 17-143 None
A0A1Y3ET03 10-119 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.