DPCstruct | MC23907

Metacluster Properties and Pfam Annotations

Number of structural domains322
Mean domain length (aa)140 ± 23 aa
Standard deviation of domain lengths22.52
Length coefficient of variation0.16
Mean AlphaFold2 pLDDT confidence score79.45
Mean fraction of residues predicted as intrinsically disordered0.20
Mean length-normalized TM-Score0.65
Mean intra-cluster local Distance Difference Test score0.60
Mean intra-cluster sequence similarity (%)17.07
Pfam Score95.86
Assigned Pfam label(s) PF01584- CL0025- CL0304

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A2R7S2M6 5-103 AEPALELISFCIGEQEFCIDVKTVREIRGWTPATPIPHAPGYLKGVINLRGAIMPVIDLRNRLGLGVTIPETRHVIVVVECQDRLAG…
A0A6M4IJS0 2-118 LVVASDRDAFGIPVEQVREVIRSAALRRVPGSPPVLRGIVNVRGGIVTVLDLQALLSGERAVTAGSVVLLEYGSRLIGLAVHAVHDV…
A0A1G3MYG8 136-282 None
A0A1P8WKK1 1-100 None
A0A2A2FKE9 22-166 None
A0A655UCU2 91-225 None
A0A3M0Y9K4 709-851 None
A0A832A2Q4 76-228 None
A0A6J6RAV8 69-208 None
A0A1F3Y257 559-690 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.