DPCstruct | MC23887

Metacluster Properties and Pfam Annotations

Number of structural domains50
Mean domain length (aa)133 ± 25 aa
Standard deviation of domain lengths25.08
Length coefficient of variation0.19
Mean AlphaFold2 pLDDT confidence score76.21
Mean fraction of residues predicted as intrinsically disordered0.41
Mean length-normalized TM-Score0.72
Mean intra-cluster local Distance Difference Test score0.80
Mean intra-cluster sequence similarity (%)43.42
Pfam Score100.00
Assigned Pfam label(s) CL0257

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A2C5ZS10 146-247 KFWQTQPVPRFDEGTRKTVSEGPLREQRVEDVSTEAQPLVDGFEWVTMDLEDDGEMKEVYQLLNGHYVEDDEAMFRFNYSPSILRWQ…
A0A815TPB2 28-137 EKSASKQEWKFWQTQPVPTIGTKIDTTNIGPIESNKSVDEIRQEPYELPNGFFWDDIDIHVDEQLQELCTFLDEHYIEDDGNNFRLK…
A0A438EWM4 2-112 None
A0A6V7UI18 5-102 None
A0A1R1XFU3 15-164 None
A0A673JYR1 57-214 None
L8GYB0 288-432 None
A0A421J377 1-123 None
A0A6V7Y3V2 1-112 None
A0A7I2V3U5 61-199 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.