DPCstruct | MC23849

Metacluster Properties and Pfam Annotations

Number of structural domains290
Mean domain length (aa)205 ± 50 aa
Standard deviation of domain lengths49.55
Length coefficient of variation0.24
Mean AlphaFold2 pLDDT confidence score82.37
Mean fraction of residues predicted as intrinsically disordered0.24
Mean length-normalized TM-Score0.46
Mean intra-cluster local Distance Difference Test score0.43
Mean intra-cluster sequence similarity (%)11.67
Pfam Score57.58
Assigned Pfam label(s) PF07946- PF11354- PF11335

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A7V8YHD0 19-167 YGTIHQGGPGVAKNLISGDVPTPDGPRQAYVFDHEQAGRLNSVLVAVQVQGQLPAAVELRLPSAPLPDDAGLDLLEPVGLRYAFVSD…
A0A1X0YCW9 25-236 ILGTKNLKREKAVRKEAQAFGYIANDKNNVKKLDDIPDFFLLAPQGKHERFLQIRNIINGYFDNIEFVMFDYMSTYSKGRTNIITAL…
A0A7W0QG31 211-375 None
A0A7C6WEG2 2-345 None
A0A7K3WFL4 186-363 None
A0A7C5J612 26-216 None
A0A1P8WAE6 45-302 None
A0A847PDA8 84-332 None
S9SIW4 7-201 None
A0A5N9AI22 61-269 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.