DPCstruct | MC23829

Metacluster Properties and Pfam Annotations

Number of structural domains1219
Mean domain length (aa)115 ± 21 aa
Standard deviation of domain lengths20.68
Length coefficient of variation0.18
Mean AlphaFold2 pLDDT confidence score78.01
Mean fraction of residues predicted as intrinsically disordered0.32
Mean length-normalized TM-Score0.55
Mean intra-cluster local Distance Difference Test score0.57
Mean intra-cluster sequence similarity (%)14.35
Pfam Score95.13
Assigned Pfam label(s) PF16273- CL0052- CL0552- PF12999- PF14913

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
V4U570 92-217 None
A0A812XSM9 360-492 None
A0A6L2PHW2 25-141 None
K5X8A2 287-439 None
A0A166DZV3 1-136 None
A0A423SDN5 46-171 None
A0A0B1P8P2 4-128 None
Q0D137 204-329 None
A0A1Y1JNB1 187-308 None
A0A7K2WGA6 184-262 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.