DPCstruct | MC23829

Metacluster Properties and Pfam Annotations

Number of structural domains1219
Mean domain length (aa)115 ± 21 aa
Standard deviation of domain lengths20.68
Length coefficient of variation0.18
Mean AlphaFold2 pLDDT confidence score78.01
Mean fraction of residues predicted as intrinsically disordered0.32
Mean length-normalized TM-Score0.55
Mean intra-cluster local Distance Difference Test score0.57
Mean intra-cluster sequence similarity (%)14.35
Pfam Score95.13
Assigned Pfam label(s) PF16273- CL0052- CL0552- PF12999- PF14913

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A4Y2E1K1 114-226 None
A0A2N0NQ62 331-445 None
A0A3B3B5G4 150-250 None
C8XCW0 315-395 None
A0A1Y2C2L2 159-285 None
A0A812N5G6 316-399 None
A0A6A3IID6 101-195 None
A0A6A1UJ15 604-712 None
A0A812SLA7 61-169 None
A0A812RDA8 404-507 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.