DPCstruct | MC23827

Metacluster Properties and Pfam Annotations

Number of structural domains429
Mean domain length (aa)359 ± 81 aa
Standard deviation of domain lengths80.63
Length coefficient of variation0.22
Mean AlphaFold2 pLDDT confidence score79.85
Mean fraction of residues predicted as intrinsically disordered0.23
Mean length-normalized TM-Score0.51
Mean intra-cluster local Distance Difference Test score0.46
Mean intra-cluster sequence similarity (%)15.70
Pfam Score95.00
Assigned Pfam label(s) PF08619- CL0142- CL0063- CL0020- CL0236

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A7S3C563 273-689 None
A0A4P5Y592 1-435 None
A0A6L5D1B7 170-600 None
A0A0K6G9B8 287-744 None
A0A4Q4XB59 248-626 None
D8F2C3 19-423 None
A0A1I7VT24 2-317 None
A0A6I9XRY4 220-535 None
A0A7J9PNK7 20-357 None
A0A7C8QGE4 10-368 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.