DPCstruct | MC23827

Metacluster Properties and Pfam Annotations

Number of structural domains429
Mean domain length (aa)359 ± 81 aa
Standard deviation of domain lengths80.63
Length coefficient of variation0.22
Mean AlphaFold2 pLDDT confidence score79.85
Mean fraction of residues predicted as intrinsically disordered0.23
Mean length-normalized TM-Score0.51
Mean intra-cluster local Distance Difference Test score0.46
Mean intra-cluster sequence similarity (%)15.70
Pfam Score95.00
Assigned Pfam label(s) PF08619- CL0142- CL0063- CL0020- CL0236

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A6P7UIY4 185-657 None
A0A498JR95 85-479 None
A0A7J4B1A1 10-303 None
A0A183ELT6 7-309 None
A0A645B680 2-320 None
A0A421ADE1 23-400 None
A0A5E4MVY8 6-303 None
A0A835I9K6 146-696 None
T1ITF2 135-597 None
T1IHD5 207-541 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.