DPCstruct | MC23827

Metacluster Properties and Pfam Annotations

Number of structural domains429
Mean domain length (aa)359 ± 81 aa
Standard deviation of domain lengths80.63
Length coefficient of variation0.22
Mean AlphaFold2 pLDDT confidence score79.85
Mean fraction of residues predicted as intrinsically disordered0.23
Mean length-normalized TM-Score0.51
Mean intra-cluster local Distance Difference Test score0.46
Mean intra-cluster sequence similarity (%)15.70
Pfam Score95.00
Assigned Pfam label(s) PF08619- CL0142- CL0063- CL0020- CL0236

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A8A7WED6 187-602 None
A0A816YBY6 127-375 None
A0A6A0ACM0 2-242 None
A0A0L7KQ60 48-480 None
A0A453HWS8 4-274 None
A0A151NWR1 133-540 None
A0A7S0ND94 11-374 None
A0A7S2DQD7 5-305 None
A0A261EW17 2-312 None
A0A4P0YE20 3-325 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.