DPCstruct | MC23827

Metacluster Properties and Pfam Annotations

Number of structural domains429
Mean domain length (aa)359 ± 81 aa
Standard deviation of domain lengths80.63
Length coefficient of variation0.22
Mean AlphaFold2 pLDDT confidence score79.85
Mean fraction of residues predicted as intrinsically disordered0.23
Mean length-normalized TM-Score0.51
Mean intra-cluster local Distance Difference Test score0.46
Mean intra-cluster sequence similarity (%)15.70
Pfam Score95.00
Assigned Pfam label(s) PF08619- CL0142- CL0063- CL0020- CL0236

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A4Q5HF06 2-321 KKIIEWFINLYAIWIILAFIVGYLYPGAFMWFTKGSWMTLALAVVMLSMGLTLRVEDFKALFATPRVVLIAAISQYTIMPLSGWLVA…
A0A7C0ZUK0 23-394 EYLSRKHIPMVLGELFLGVLLAAIFGVISEDLLEACGSEIYDVFSLLGIMFLMFISGLETDVGYLQRSLKYGLSVALLGSVVPFALV…
A0A432FFC5 6-331 None
A0A177KUH8 4-283 None
A0A2I0NCQ8 155-378 None
A0A6A6L5R3 227-534 None
A0A3M1B951 30-516 None
A0A672Q737 2-280 None
A0A0G4HHY8 293-720 None
A0A378AL23 180-508 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.