DPCstruct | MC23820

Metacluster Properties and Pfam Annotations

Number of structural domains930
Mean domain length (aa)163 ± 31 aa
Standard deviation of domain lengths31.01
Length coefficient of variation0.19
Mean AlphaFold2 pLDDT confidence score82.72
Mean fraction of residues predicted as intrinsically disordered0.22
Mean length-normalized TM-Score0.51
Mean intra-cluster local Distance Difference Test score0.46
Mean intra-cluster sequence similarity (%)14.25
Pfam Score71.61
Assigned Pfam label(s) PF05678- PF19445- CL0029- CL0109- PF15253

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A354GTL3 14-126 QDAGVRQVIEQAWLDSLANDPILRHEEGGWIYLDLTSGVLSFIRAIAGATSGISLSAPPTVAGAVVVGKFHTHPNPEIEGWTTGPSP…
X1X464 6-182 DQLTDVFISDEVLLMCHNLALLTEKEEVAALLIGQKIIHENGITVSVTALSIPPRGEIKKDRVEIMSEDLVNAMEDAKHFSRVKGAN…
A0A7T1MFI9 38-188 None
A0A7T1HW96 2-157 None
A0A2B4SEM7 404-576 None
A0A0F9UKP2 16-125 None
A0A1F6BF25 37-161 None
A0A377CF06 231-341 None
A0A3P9K1K3 4-195 None
A0A373B2Z9 394-521 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.