DPCstruct | MC23819

Metacluster Properties and Pfam Annotations

Number of structural domains142
Mean domain length (aa)465 ± 83 aa
Standard deviation of domain lengths82.93
Length coefficient of variation0.18
Mean AlphaFold2 pLDDT confidence score84.58
Mean fraction of residues predicted as intrinsically disordered0.22
Mean length-normalized TM-Score0.35
Mean intra-cluster local Distance Difference Test score0.40
Mean intra-cluster sequence similarity (%)15.51
Pfam Score50.17
Assigned Pfam label(s) CL0040- PF00221- CL0404- PF19300

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A2E5V010 257-669 None
M7TMC8 61-620 None
A0A823A5I8 458-1003 None
A0A8A6QYU9 1-377 None
A0A0E9NP56 26-526 None
V4XE75 394-903 None
A0A3M5E3D8 206-599 None
A0A811NJZ5 2-436 None
A0A1A9QGF6 9-354 None
A0A1D6E5Z1 41-408 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.