DPCstruct | MC23819

Metacluster Properties and Pfam Annotations

Number of structural domains142
Mean domain length (aa)465 ± 83 aa
Standard deviation of domain lengths82.93
Length coefficient of variation0.18
Mean AlphaFold2 pLDDT confidence score84.58
Mean fraction of residues predicted as intrinsically disordered0.22
Mean length-normalized TM-Score0.35
Mean intra-cluster local Distance Difference Test score0.40
Mean intra-cluster sequence similarity (%)15.51
Pfam Score50.17
Assigned Pfam label(s) CL0040- PF00221- CL0404- PF19300

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A7Z9PPD3 2-351 LIGEGEVFHHGQRRPTPDVFSEFGIKPVTLVAKEGLALINGTHLMCGRFALIAQDLRRVTNAAFIANAMSIDAARASHGYLDSRVYA…
X1WZ00 222-689 SLAALMIGAVVGSGVAAAKLSPQRWVRWLGEAYSTVFRGIPELLVIYLFYFGGSGLITLVGQMFGADGFIEAPPFLIGALAIGLISG…
A0A812ILL8 360-816 None
A0A7X3T872 6-415 None
A0A2S8BD42 34-525 None
A0A135VMM9 19-456 None
A0A2A2K5X3 309-869 None
K5UM21 209-676 None
A0A1V5R4T2 35-556 None
A0A814QGP2 2-493 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.