DPCstruct | MC23774

Metacluster Properties and Pfam Annotations

Number of structural domains15
Mean domain length (aa)89 ± 8 aa
Standard deviation of domain lengths7.55
Length coefficient of variation0.08
Mean AlphaFold2 pLDDT confidence score92.32
Mean fraction of residues predicted as intrinsically disordered0.16
Mean length-normalized TM-Score0.89
Mean intra-cluster local Distance Difference Test score0.84
Mean intra-cluster sequence similarity (%)41.69
Pfam Score0.00
Assigned Pfam label(s) UNKNOWN

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A645F360 2-95 GEFMKLTKIPIIIYYGDFIPEQPSDNPGIDGWRARLEMAKLWRDTVNKYGGDVTLIHLPEIGIKGNTHFPFSDLNNVEIADLLSEWL…
W4UY73 121-211 FMKLTQIPIVMYFGDYIPEEVTHELGAENWRTRLTLGRLFVEAVNRHGGDATLVELPKIGIYGNTHFLMSDLNNIEIADLLSAWMKE…
A0A6S7DF58 4-79 None
A0A4Q0M2P2 43-140 None
A0A327XTF2 44-136 None
A0A6J5DNA9 14-103 None
A0A1Y4D660 1-87 None
A0A7K3K9X2 474-563 None
A0A7X4H9B3 488-582 None
J1GU74 4-79 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.