DPCstruct | MC23754

Metacluster Properties and Pfam Annotations

Number of structural domains84
Mean domain length (aa)193 ± 32 aa
Standard deviation of domain lengths32.49
Length coefficient of variation0.17
Mean AlphaFold2 pLDDT confidence score86.75
Mean fraction of residues predicted as intrinsically disordered0.18
Mean length-normalized TM-Score0.70
Mean intra-cluster local Distance Difference Test score0.68
Mean intra-cluster sequence similarity (%)35.10
Pfam Score100.00
Assigned Pfam label(s) CL0059

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A024SC02 121-348 LLGGIVITWYVTKTPIPDAYATEIKNYITARAHPEDGGWGLHIEGESTVFGTAMNYIVLRLIGVDAEDPVMVKARATLHKMGGAVNA…
A0A446UXH5 8-198 HQNEDGGWGMHIEGHSTMIGSSLNYVALRLLGEGPNGGDGAIEKGRNWILDHGGATFAPSWGKFWLLVLGAYDWSGTNPVPPELWLL…
A0A0D3C1E0 3-171 None
A0A067KLI9 1-164 None
A0A835IJW9 455-707 None
A0A5N5JBD8 29-209 None
A0A5N5J6F1 228-433 None
A0A067JM13 131-309 None
A0A7V8VDQ5 60-274 None
A0A5A7QXW6 391-634 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.