DPCstruct | MC2374

Metacluster Properties and Pfam Annotations

Number of structural domains10
Mean domain length (aa)178 ± 11 aa
Standard deviation of domain lengths11.40
Length coefficient of variation0.06
Mean AlphaFold2 pLDDT confidence score89.92
Mean fraction of residues predicted as intrinsically disordered0.40
Mean length-normalized TM-Score0.79
Mean intra-cluster local Distance Difference Test score0.68
Mean intra-cluster sequence similarity (%)31.66
Pfam Score0.00
Assigned Pfam label(s) UNKNOWN

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A7V2QVH1 244-408 RAHENLYSYKDYDSPLSDRVREGHEDIDGDIELETHNPYIYVKAEGHAVYGDLRWEEKGFPGGDGVVYRYTGQAEEPQNGNDRNVGY…
A0A1H9XVU5 1-164 MAHSDFYSYVPAGSPYRNGSETIDGTLLLVGGRPATFQEAKGHGLYRWNGGDFPGGDGVVYQPAATGEVPSGGNDRTVGYRLVNTLE…
A0A3A0ALY5 158-339 None
A0A6V6YEP1 19-187 None
A0A2T4VKU4 134-314 None
A0A6N6S858 273-464 None
A0A2D0N0T2 178-372 None
A0A810M2K4 1-166 None
A0A2A8XW85 129-304 None
A0A524ACZ8 132-323 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.