DPCstruct | MC2373

Metacluster Properties and Pfam Annotations

Number of structural domains31
Mean domain length (aa)74 ± 10 aa
Standard deviation of domain lengths10.30
Length coefficient of variation0.14
Mean AlphaFold2 pLDDT confidence score82.65
Mean fraction of residues predicted as intrinsically disordered0.27
Mean length-normalized TM-Score0.75
Mean intra-cluster local Distance Difference Test score0.73
Mean intra-cluster sequence similarity (%)31.79
Pfam Score0.00
Assigned Pfam label(s) UNKNOWN

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A1H9V1Q2 2-65 AVLLVRKRAGVVGETQRTCHLVPVPDGDTPLALTAYCGELIRQGEAELLDRPSGMPCVDCLFRV
A0A1H0SYW1 9-84 IVPILLVRLRPGPGVRETQRVVHVVPVPETDGVLPDVLTAWCAFKIQPGAAEVLERFAGMPCERCLAKAPTPEGKR
A0A5M7B5X3 2-68 None
W7T2A8 2-70 None
A0A1H8YQN0 49-118 None
A0A229TI75 57-127 None
A0A1Q9V5T2 2-72 None
A0A1I1ZCT8 3-67 None
A0A5N8X8E0 2-76 None
A0A853ATT1 4-68 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.