DPCstruct | MC23709

Metacluster Properties and Pfam Annotations

Number of structural domains28
Mean domain length (aa)195 ± 14 aa
Standard deviation of domain lengths13.60
Length coefficient of variation0.07
Mean AlphaFold2 pLDDT confidence score91.51
Mean fraction of residues predicted as intrinsically disordered0.33
Mean length-normalized TM-Score0.88
Mean intra-cluster local Distance Difference Test score0.85
Mean intra-cluster sequence similarity (%)46.31
Pfam Score97.37
Assigned Pfam label(s) PF02814- CL0036

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A378A8S9 66-267 SSDSQAMGRVGENWLRVVQTAHAMKVARGKLPEDSDGNDNFRVLRYVAKLTINPAIAHGVSHIIGSVEVGKMADLVLWDPRSFGAKP…
F9FUC7 5-183 SQAMGRSAEVLTCTWKAAHKNKVQRGPLDEDKDTGADNFRVKRFISKYTINPAITQGISHAVGSIEAGKLADLAIWDPAEFGTKPFQ…
A0A6A3B9W3 383-579 None
A0A3S4NQ97 472-657 None
G8S4B6 319-508 None
A0A7K2XYX2 77-275 None
A0A066YSE0 826-1024 None
A0A6A5LA80 360-555 None
A0A1Q9D7U7 30-251 None
A0A263HEL9 323-518 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.