DPCstruct | MC23677

Metacluster Properties and Pfam Annotations

Number of structural domains18
Mean domain length (aa)372 ± 56 aa
Standard deviation of domain lengths56.43
Length coefficient of variation0.15
Mean AlphaFold2 pLDDT confidence score72.04
Mean fraction of residues predicted as intrinsically disordered0.39
Mean length-normalized TM-Score0.58
Mean intra-cluster local Distance Difference Test score0.74
Mean intra-cluster sequence similarity (%)32.52
Pfam Score100.00
Assigned Pfam label(s) CL0125

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
I0YQT2 1-290 MTVTALVASLNPAIVARQNTGVDSEEIQVLQKLLLEEIRSKHPEAMYPAALCTLADLLEIEEQDGLDKAIASGSEQEAVARCTCRSE…
A0A6P6H659 24-398 VAFMVCAINPSIDLHTDSLELLQLQQKLLWLLYDLGHLERYPMALGNLADLEELEPTPGRPDPLTLYHKGIASAKTYYRDEHIYPYM…
A0A812AST4 1-405 None
A0A5K3F810 440-806 None
A0A6G0HIB0 126-470 None
A0A177AWE0 228-537 None
A0A4Y7N276 12-335 None
A0A437CBM0 9-400 None
A0A132AAT2 412-818 None
S4REI0 2-317 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.