DPCstruct | MC23671

Metacluster Properties and Pfam Annotations

Number of structural domains7
Mean domain length (aa)59 ± 3 aa
Standard deviation of domain lengths2.55
Length coefficient of variation0.04
Mean AlphaFold2 pLDDT confidence score92.41
Mean fraction of residues predicted as intrinsically disordered0.47
Mean length-normalized TM-Score0.95
Mean intra-cluster local Distance Difference Test score0.96
Mean intra-cluster sequence similarity (%)81.86
Pfam Score87.50
Assigned Pfam label(s) PF00010- PF01586

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A815P8J3 194-249 VDRRKAATMRERRRLRKVNEAFETLKRRTCPNPSQRLPKVEILRNAIEYIENLEDL
A0A2H1C6J6 3-58 VDRRKAATMRERRRLRKVNEAFETLKRRTCANPNQRMPKVEILRNAIDYIENLEEM
A0A7E6FUT6 221-276 None
A0A1B0AVC0 153-212 None
A0A7M4E604 79-140 None
A0A4Z2G6F1 102-163 None
A0A4W3GAX1 6-64 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.