DPCstruct | MC23667

Metacluster Properties and Pfam Annotations

Number of structural domains55
Mean domain length (aa)175 ± 37 aa
Standard deviation of domain lengths37.01
Length coefficient of variation0.21
Mean AlphaFold2 pLDDT confidence score79.15
Mean fraction of residues predicted as intrinsically disordered0.24
Mean length-normalized TM-Score0.65
Mean intra-cluster local Distance Difference Test score0.68
Mean intra-cluster sequence similarity (%)26.20
Pfam Score98.08
Assigned Pfam label(s) CL0123- CL0040

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A6G3MIH0 7-176 ILDEIMNELKISPTINSKKFSDTKELDHSMVVGQIMSLSSVPDLVSVSKETTTHWTLTTEGEDIVKNGSYEYRLYSSIPETGIFIKE…
A0A2U1PEM0 2-186 AEDAILTYLDKNELIVDSGEFAVEVGISHEEIVNAIKSLMYSKSVNAQDIKKESCKLTDEGKTYAAKGSPEYQLFMAIPPEGITIVE…
A0A818HB37 18-214 None
N1R4Z5 85-208 None
A0A2H5RA39 7-170 None
U6MWQ5 1-263 None
A0A453PNF5 15-172 None
A0A453PNK2 52-216 None
A0A1X7TUR4 8-172 None
A0A5B7D429 6-267 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.