DPCstruct | MC23662

Metacluster Properties and Pfam Annotations

Number of structural domains24
Mean domain length (aa)113 ± 19 aa
Standard deviation of domain lengths18.93
Length coefficient of variation0.17
Mean AlphaFold2 pLDDT confidence score85.80
Mean fraction of residues predicted as intrinsically disordered0.29
Mean length-normalized TM-Score0.80
Mean intra-cluster local Distance Difference Test score0.80
Mean intra-cluster sequence similarity (%)46.23
Pfam Score90.38
Assigned Pfam label(s) CL0039- PF20979

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A2I0RX55 94-244 RPVIARAQVAVAQKEGCFAVSHGCTGKGNDQVRFELAFYALQPSIKVIAPWRDPAFYERFKGRQDLLDYATEKGIPVTSTKRKPWSM…
A0A2U1P2J2 2-108 TLPHGCTGKGNDQVRFELTFIALNPDLHVVAPWREWDITGREDAIEYAKKHNVPVPVTKKSIYSRDRNLWHLSHEVPITRINTMFPL…
A0A5N6NWS3 183-313 None
A0A0R0IGZ2 2-94 None
A0A7V1K436 4-93 None
A0A6L5C892 370-460 None
A0A5J5CR08 106-240 None
A0A812IRJ5 350-443 None
A0A7R9KWP3 31-173 None
A0A2M6YG27 118-221 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.