DPCstruct | MC23628

Metacluster Properties and Pfam Annotations

Number of structural domains39
Mean domain length (aa)140 ± 18 aa
Standard deviation of domain lengths18.25
Length coefficient of variation0.13
Mean AlphaFold2 pLDDT confidence score84.80
Mean fraction of residues predicted as intrinsically disordered0.23
Mean length-normalized TM-Score0.57
Mean intra-cluster local Distance Difference Test score0.82
Mean intra-cluster sequence similarity (%)44.39
Pfam Score100.00
Assigned Pfam label(s) CL0220

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A195C798 1-106 MEEMLFEADCRNALETHKCSFNGLDYLAEILWNRNLRHPSRLYTWQDVFNIPQFKLWLKLHPRPIYPNSWLWTKEEAALHIQRYVRG…
U3KHZ4 6-141 LEFYIFPVLLPGLAALLHEAEKEKCFEGKRTKFIPSDFLTEWLYNKNPKRKDESFTELFSIPFVKDWLKDRPRPPIPLSLLLSEEEA…
A0A2H1BW47 3-113 None
A0A7J5YAA2 93-249 None
A0A4U1FFR2 13-133 None
A0A665V443 2-138 None
A0A6P4XIT0 81-223 None
A0A7M5X4Q8 24-171 None
W5M4S8 2-146 None
A0A5J4P138 54-187 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.