DPCstruct | MC2362

Metacluster Properties and Pfam Annotations

Number of structural domains23
Mean domain length (aa)80 ± 6 aa
Standard deviation of domain lengths6.44
Length coefficient of variation0.08
Mean AlphaFold2 pLDDT confidence score93.14
Mean fraction of residues predicted as intrinsically disordered0.20
Mean length-normalized TM-Score0.88
Mean intra-cluster local Distance Difference Test score0.88
Mean intra-cluster sequence similarity (%)63.83
Pfam Score100.00
Assigned Pfam label(s) CL0063

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A4S8IMD2 343-423 PILDQMLLEQTTENVVWTPSKVIVRLGKEINDESSYLYWAYKNNVSVYCPALTDGSLGDMLYCHSVRNPGLLIDIVQDIRA
A0A6P5HN42 1-76 MLTLDTMLAEQEEKDMIWTPSKVIARLGVEINNEHLIYYGAEKNNILVLSSTLSDGNLHFYRNPGLIIDIISDLNL
A0A259J9L3 297-381 None
A0A813VPC6 226-302 None
A0A1P8BA27 2-76 None
A0A453DTU1 238-316 None
A0A4W6DZN1 55-132 None
A0A368FQR2 35-113 None
A0A835N9P5 1002-1083 None
A0A433QJP8 740-817 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.