DPCstruct | MC23613

Metacluster Properties and Pfam Annotations

Number of structural domains88
Mean domain length (aa)115 ± 25 aa
Standard deviation of domain lengths24.94
Length coefficient of variation0.22
Mean AlphaFold2 pLDDT confidence score71.78
Mean fraction of residues predicted as intrinsically disordered0.34
Mean length-normalized TM-Score0.65
Mean intra-cluster local Distance Difference Test score0.74
Mean intra-cluster sequence similarity (%)30.12
Pfam Score99.14
Assigned Pfam label(s) PF03172- PF01342

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A183DTL4 3-75 LFQVRCGQLVARLHVEKFVCPGIHQPCIELDGELISPKEFTVRANKDKQKDWKGSIRIGKSNMRALMEMKTLD
A0A7E6DPQ0 16-127 DSAKYENGGEPLKASTPAVKRKTGTGQQPGVNVNFEAEILPVTCKENMGLLIKRKLERGATRKCIRIEDGNWFTPGEFEIRGGHEKA…
A0A670IJJ5 465-549 None
M3W7Z9 461-588 None
A0A6P7DQY2 509-645 None
A0A669DEE8 1-88 None
A0A7M5UYH2 165-336 None
A0A6S7FWD6 107-232 None
A9JR84 11-156 None
H3BC61 4-81 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.