DPCstruct | MC23584

Metacluster Properties and Pfam Annotations

Number of structural domains17
Mean domain length (aa)230 ± 60 aa
Standard deviation of domain lengths60.13
Length coefficient of variation0.26
Mean AlphaFold2 pLDDT confidence score74.94
Mean fraction of residues predicted as intrinsically disordered0.30
Mean length-normalized TM-Score0.68
Mean intra-cluster local Distance Difference Test score0.73
Mean intra-cluster sequence similarity (%)27.97
Pfam Score94.07
Assigned Pfam label(s) CL0182- PF03105

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A7R9PDQ7 3-193 AMLYLVVEEAPSAESVEPEIITRHFANFDEHFFHFCDSELKKINTFYSEKLAEATRKFATLQNELQISLANRASAKNKNQGKPRIQT…
A0A182H5L7 154-355 RTVHEYEMKAQLYAAVEQSPSAELVDPEVLTRYFAKFDEQFFHFCDSELAKINTFYSEKLAEATRKFANLRTELSETLELEESTKKK…
A0A2G4SKE0 24-206 None
A0A2H1BZC7 1-272 None
A0A1C7M5B4 1-222 None
A0A183SPM8 1-281 None
A0A7S0GC00 2-297 None
A0A2H2IV39 110-278 None
A0A6F9AL34 46-238 None
A0A1B0FK38 16-178 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.