DPCstruct | MC23576

Metacluster Properties and Pfam Annotations

Number of structural domains26
Mean domain length (aa)185 ± 21 aa
Standard deviation of domain lengths20.75
Length coefficient of variation0.11
Mean AlphaFold2 pLDDT confidence score83.67
Mean fraction of residues predicted as intrinsically disordered0.18
Mean length-normalized TM-Score0.77
Mean intra-cluster local Distance Difference Test score0.71
Mean intra-cluster sequence similarity (%)30.84
Pfam Score0.00
Assigned Pfam label(s) UNKNOWN

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
M5XHY4 6-156 IEMNDLDKHPNFLAEKYLRKNLPSLNKPRIFYETLVIETKSINIVHRHRGENANTIAFSKIQILNVISLEEWDPSPERDYKKAWEYV…
A0A830BS68 2-161 YQAILEDNDSAFFKHFKEKEETTYSTCKILRGLAPSEWKHSISAPIRLSQKYAENSWAFIPYNYWDYQQAWFNSFFIQNKNEKHSWL…
A0A836J305 506-699 None
M1DWK7 18-203 None
H2KWE4 161-366 None
A0A151T5L5 6-164 None
M1DZ48 530-706 None
A0A3S3NGC3 302-513 None
A0A2N9IG48 1-216 None
A0A5N6P372 77-285 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.