DPCstruct | MC23575

Metacluster Properties and Pfam Annotations

Number of structural domains213
Mean domain length (aa)112 ± 20 aa
Standard deviation of domain lengths20.01
Length coefficient of variation0.18
Mean AlphaFold2 pLDDT confidence score69.42
Mean fraction of residues predicted as intrinsically disordered0.33
Mean length-normalized TM-Score0.63
Mean intra-cluster local Distance Difference Test score0.71
Mean intra-cluster sequence similarity (%)26.98
Pfam Score98.00
Assigned Pfam label(s) CL0109- CL0617- PF13963- CL0219- PF13960

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A445AFC1 109-228 None
A0A811QM69 4-130 None
A0A811QTG6 2-144 None
A0A1S3EI55 37-172 None
Q5W6P3 1-134 None
Q60DA1 125-253 None
Q60EC3 7-137 None
A0A7J7M1A6 4-137 None
A0A7J7M964 67-165 None
A0A7J7MFT8 1-144 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.